Glycoconjugate Vaccines

Authors

  • A. Fleischhackerová Department of Immunochemistry of Glycoconjugates, Institute of Chemistry, Slovak Academy of Sciences, Bratislava, Slovakia
  • P. Farkaš Department of Immunochemistry of Glycoconjugates, Institute of Chemistry, Slovak Academy of Sciences, Bratislava, Slovakia
  • S. Bystrický Department of Immunochemistry of Glycoconjugates, Institute of Chemistry, Slovak Academy of Sciences, Bratislava, Slovakia

Keywords:

glycoconjugate, conjugation, polysaccharide, antigen, vaccine, lymphocytes, immunological memory

Abstract

This paper provides an overview of carbohydrate-based glycoconjugate vaccines used in clinical practice. The structures of capsular polysaccharides mostly used in vaccine design and preparation of glycoconjugates are highlighted. Molecular mechanisms by which glycoconjugates are able to elicit T-cell-dependent immune response are mentioned.

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Published

2014-02-15

How to Cite

Fleischhackerová, A., Farkaš, P., & Bystrický, S. (2014). Glycoconjugate Vaccines. Chemické Listy, 108(2), 120–126. Retrieved from http://w.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/551

Issue

Vol. 108 No. 2 (2014)

Section

Articles