Hot-stage Microscopy in Pharmaceutical Industry

Authors

  • M. Šimek Department of Solid State Chemistry, Faculty of Chemical Technology, University of Chemistry and Technology, Prague | Zentiva, k.s., Prague
  • B. Kratochvíl Department of Solid State Chemistry, Faculty of Chemical Technology, University of Chemistry and Technology, Prague

Keywords:

hot-stage microscopy, API, drug, analysis, pharmacy

Abstract

Hot-stage microscopy (HSM) affords combined light microscopy and thermal analysis, enabling the study of materials as a function of temperature and time. This combination involves visual examination and gives valuable information on the compound regarding its melting point, phase transformation, new phase formation, solid-state interactions, particle and solid dispersions analysis during heating. HSM gives a unique opportunity to visually follow thermal changes. Model cases of HSM application show its current usage in pharmaceutical industry thus supporting and inspiring its research.

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Published

2015-09-15

How to Cite

Šimek, M., & Kratochvíl, B. (2015). Hot-stage Microscopy in Pharmaceutical Industry. Chemické Listy, 109(9), 687–692. Retrieved from http://w.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/313

Issue

Vol. 109 No. 9 (2015)

Section

Articles